Effect of exercise on uterine blood flow in the pregnant Pygmy goat.
Effect of exercise on uterine blood flow in the pregnant Pygmy goat.
复制标题
运动对怀孕侏儒山羊子宫血流的影响。
DOI：
10.1152/ajpheart.1984.246.2.h207
复制
发表时间：
1984
期刊：
影响因子：
--
通讯作者：
McKean,TA
中科院分区：
文献类型：
--
作者：
Hohimer,AR;Bissonnette,JM;Metcalfe,J;McKean,TA
怀孕最后三分之一的侏儒山羊被训练在跑步机上以每小时2.0英里的速度行走，倾斜0-15度。将电磁流量计放置在一侧子宫动脉上，在山羊安静地站在跑步机上和运动5min的情况下进行测量。在运动过程中，所有五只动物的血流量都下降了，而且这种下降与运动水平成正比。在这些动物自愿进行的最高运动水平下，子宫动脉血流量比对照组下降了32+/-3(SE)%(P<0.001)。在另外4只动物中，使用放射性微球技术测量安静时和运动后5-7分钟的子宫血流量。在这些动物中，运动导致子宫总血流量下降18+/-10%，子叶(胎盘)血流量下降8+/-13%，而肌内膜血流量下降52+/-12%(P<0.05)。因此，怀孕的侏儒山羊子宫的非胎盘部分在运动过程中血流量大幅下降。这种血管收缩可能是由于运动本身，也可能是伴随的低碳酸血症或体温升高。参加运动的动物所生的单胞胎和双胞胎孩子出生时体重正常。
Pygmy goats in the last third of pregnancy were trained to walk on a treadmill at rates up to 2.0 mph and up an inclination of 0-15 degrees. Electromagnetic flowmeters were placed unilaterally on a uterine artery, and measurements were made while the goats were standing quietly on the treadmill and during 5 min of exercise. Blood flow fell during exercise in all five animals studied, and this reduction was proportional to the level of exertion. At the highest level of exercise that these animals would voluntarily perform, uterine artery blood flow fell by 32 +/- 3 (SE) % (P less than 0.001) from control. In four additional animals the radioactive microsphere technique was used to measure uterine blood flow at rest and after 5-7 min of exercise. In these animals, exercise caused total uterine blood flow to fall by 18 +/- 10%; cotyledonary (placental) blood flow fell by 8 +/- 13%, while myoendometrial blood flow decreased by 52 +/- 12% (P less than 0.05). Thus nonplacental portions of the pregnant Pygmy goat uterus suffer major reductions in blood flow during exercise. This vasoconstriction may be due to exercise per se or to concomitant hypocapnia or hyperthermia. Singleton and twin kids born to animals that exercised were of normal birth weight.