X-ray phase-contrast microscopy and microtomography
X-ray phase-contrast microscopy and microtomography
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DOI:
10.1364/oe.11.002289
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发表时间:
2003-09-22
期刊:
影响因子:
3.8
通讯作者:
Wilkins, SW
中科院分区:
文献类型:
--
作者:
Mayo, SC;Davis, TJ;Wilkins, SW
In-line phase contrast enables weakly absorbing specimens to be imaged successfully with x-rays, and greatly enhances the visibility of fine scale structure in more strongly absorbing specimens. This type of phase contrast requires a spatially coherent beam, a condition that can be met by a microfocus x-ray source. We have developed an x-ray microscope, based on such a source, which is capable of high resolution phase-contrast imaging and tomography. Phase retrieval enables quantitative information to be recovered from phase-contrast microscope images of homogeneous samples of known composition and density, and improves the quality of tomographic reconstructions. (C) 2003 Optical Society of America