Possible circulation of H5N1 avian influenza viruses in healthy ducks on farms in northern Vietnam
Possible circulation of H5N1 avian influenza viruses in healthy ducks on farms in northern Vietnam
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DOI：
10.1111/j.1348-0421.2009.00170.x
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发表时间：
2010-01-01
影响因子：
2.6
通讯作者：
Otsuki, Koichi
中科院分区：
文献类型：
--
作者：
Takakuwa, Hiroki;Yamashiro, Tetsu;Otsuki, Koichi
为了估计 2006 年 10 月至 11 月期间没有 H5N1 疫情爆发期间家鸭中 A 亚型 H5N1 病毒的流行情况，收集了 1106 只在越南北部饲养的健康鸭子。将所有喉咙和泄殖腔样本接种到含胚蛋中，在 13 只鸭子中分离出 H3N8 亚型病毒，但没有分离出 H5N1 病毒。血清学分析表明，5 只鸭子 (0.45%) 单独产生了 H5N1 亚型特异性血凝素抑制抗体和神经氨酸酶抑制抗体以及抗非结构蛋白 1 抗体。结果表明，当没有明显的 H5N1 疫情爆发时，鸭子自然感染了 H5N1 病毒。
To estimate the prevalence of influenza A subtype H5N1 viruses among domestic ducks in the period between October and November 2006 when H5N1 outbreaks had been absent, 1106 healthy ducks raised in northern Vietnam were collected. Inoculation of all throat and cloacae samples into embryonated eggs resulted in the isolation of subtype H3N8 in 13 ducks, but not H5N1 viruses. Serological analyses demonstrated that five ducks (0.45%) solely developed H5N1 subtype-specific hemagglutinin-inhibiting and neuraminidase-inhibiting antibodies together with anti-non-structural protein 1 antibodies. The results suggested that the ducks were naturally infected with H5N1 viruses when obvious H5N1 outbreaks were absent.