The SYSTERS protein sequence cluster set

The SYSTERS protein sequence cluster set
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DOI:
10.1093/nar/28.1.270
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发表时间:
2000-01-01
影响因子:
14.9
通讯作者:
Vingron, M
Vingron, M
中科院分区:
生物学2区
文献类型:
--
作者:
Krause, A;Stoye, J;Vingron, M

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蛋白质序列聚类集包括将来自SWISS-PROT和PIR的所有序列分类为不相交的蛋白质家族聚类以及分层地分类为超家族和亚家族聚类。可以使用SSMAL搜索工具或传统的数据库搜索工具如BLAST或FASTA用序列搜索簇集。此外,还为每个簇生成多重比对,并使用来自蛋白质结构域家族Pfam数据库的结构域信息进行注释。基于NCBI分类法给出了聚类所涵盖的生物的分类学概述。可在http://www.dkfz-heidelberg上查询和浏览群集集。de/tbi/services/cluster/systersform。
The SYSTERS (short for SYSTEmatic Re-Searching) protein sequence cluster set consists of the classification of all sequences from SWISS-PROT and PIR into disjoint protein family clusters and hierarchically into superfamily and subfamily clusters. The cluster set can be searched with a sequence using the SSMAL search tool or a traditional database search tool like BLAST or FASTA. Additionally a multiple alignment is generated for each cluster and annotated with domain information from the Pfam database of protein domain families. A taxonomic overview of the organisms covered by a cluster is given based on the NCBI taxonomy. The cluster set is available for querying and browsing at http://www.dkfz-heidelberg. de/tbi/services/cluster/systersform.