GC-MS assay for acetaminophen in human hair segments
GC-MS assay for acetaminophen in human hair segments
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DOI：
10.1007/s11419-008-0044-z
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发表时间：
2008-05
影响因子：
2.2
通讯作者：
Takeshi Saito;S. Morita;S. Inoue;I. Yamamoto;S. Inokuchi
中科院分区：
文献类型：
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作者：
Takeshi Saito;S. Morita;S. Inoue;I. Yamamoto;S. Inokuchi
建立了人发中对乙酰氨基酚（APAP）的气相色谱-质谱分析方法。定量限低至0.1 ng/mg。测定的线性浓度范围为0.1-10 ng/mg。日间和日内变异系数均小于10%。该方法已成功地应用于实际中毒案例中APAP的毛发分析。
A detailed procedure for sensitive analysis of acetaminophen (APAP) in human hair segments by gas chromatography-mass spectrometry is reported. The limit of quantitation was as low as 0.1 ng/mg. The linear concentration range of the assay was 0.1–10 ng/mg. The interday and intraday coefficients of variation were below 10%. The method was successfully applied to hair analysis of APAP in an actual poisoning case.