An autopsy case of Mycobacterium abscessus pulmonary infection complicated with rheumatoid arthritis
An autopsy case of Mycobacterium abscessus pulmonary infection complicated with rheumatoid arthritis
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DOI：
10.2169/internalmedicine.47.1023
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发表时间：
2008-01-01
影响因子：
1.2
通讯作者：
Taguchi, Yoshio
中科院分区：
文献类型：
--
作者：
Fujita, Kumi;Tanaka, Eisaku;Taguchi, Yoshio
我们提出的情况下，一个70岁的男子诊断为脓肿分枝杆菌肺部感染合并类风湿关节炎谁是用皮质类固醇治疗。尽管按照推荐的亚胺培南、克拉霉素和阿米卡星治疗方案进行治疗，他还是死亡了。尸检显示双肺肉芽肿病变。我们认为，由于病原菌的耐药性，脓肿分枝杆菌感染可能具有致命的后果。本病例提示类风湿关节炎可能是脓疡分枝杆菌肺部感染的危险因素，但需要进一步的研究来澄清。
We present the case of a 70-year-old man diagnosed with Mycobacterium abscessus pulmonary infection complicated with rheumatoid arthritis who was treated with corticosteroids. He died despite treatment according to the recommended regimen of imipenem, clarithromycin, and amikacin. Autopsy revealed granulomatous lesions throughout the bilateral lungs. We conclude that M. abscessus infection may have a fatal outcome because of the drug resistance of the pathogen. This case suggests that rheumatoid arthritis might be a risk factor for M. abscessus pulmonary infection, but further studies are necessary for clarification.