QT interval: How to measure it and what is "normal"
QT interval: How to measure it and what is "normal"
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DOI：
10.1111/j.1540-8167.2006.00408.x
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发表时间：
2006-03-01
影响因子：
2.7
通讯作者：
Zareba, W
中科院分区：
文献类型：
--
作者：
Goldenberg, I;Moss, AJ;Zareba, W
QT间期异常长短与危及生命的室性心律失常和心源性猝死的风险增加有关。近年来，各种QT间期测量方法得到了发展，包括基于个体的复极持续时间校正、复极形态定量评估、复极动态性校正和复极变异性分析。然而，这些方法需要对电子存储的ECG数据进行计算机处理的数字信号分析，并且最常用于药物试验中复极变化的评估。在本综述中，我们将重点介绍12导联心电图QT间期的临床相关视觉和手动评估方法，这些方法可用于诊断长QT综合征（LQTS）和其他复极障碍。
Abnormally long and short QT intervals have been shown to be associated with an increased risk for life-threatening ventricular arrhythmias and sudden cardiac death. In recent years, various methods for QT-interval measurement have been developed, including individual-based corrections for repolarization duration, quantitative assessment of repolarization morphology, correction for repolarization dynamicity, and analysis of repolarization variability. However, these methods require computer-processed digital-signal analysis of electronically stored ECG data and have been used most frequently in the assessment of repolarization changes in drug trials. In the present review, we will focus on methods for clinically relevant visual and manual assessment of QT-interval duration from a 12-lead ECG, which can be utilized in day-today practice for the diagnosis of long QT syndrome (LQTS) and other repolarization disorders.