Neural Correlate of Visual Familiarity in Macaque Area V2
Neural Correlate of Visual Familiarity in Macaque Area V2
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DOI：
10.1523/jneurosci.0664-18.2018
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发表时间：
2018-10-17
影响因子：
5.3
通讯作者：
Olson, Carl R.
中科院分区：
文献类型：
--
作者：
Huang, Ge;Ramachandran, Suchitra;Olson, Carl R.
猕猴颞下皮质(ITC)的神经元对熟悉的图像的反应不如对新图像的强烈。通常认为，这种效应出现在ITC内部，因为它的神经元选择性地对复杂图像做出反应，从而以一种明确的形式编码足以将特定图像识别为熟悉的信息。然而，先前没有研究检验低阶视觉区域中的神经元是否也表现出熟悉性抑制。为了解决这个问题，我们用半计时微电极阵列记录了猕猴V2区神经元的信息，同时猴子重复观看了一组大型复杂的自然图像。我们在这里报告了V2神经元表现出熟悉抑制。这种效果会持续几天，其轨迹很好地符合一个指数函数，其速率常数类似于100次曝光。在V2中，抑制发生在图像开始后的潜伏期比其在ITC中报告的潜伏期短。
Neurons in macaque inferotemporal cortex (ITC) respond less strongly to familiar than to novel images. It is commonly assumed that this effect arises within ITC because its neurons respond selectively to complex images and thus encode in an explicit form information sufficient for identifying a particular image as familiar. However, no prior study has examined whether neurons in low-order visual areas selective for local features also exhibit familiarity suppression. To address this issue, we recorded from neurons in macaque area V2 with semichronic microelectrode arrays while monkeys repeatedly viewed a set of large complex natural images. We report here that V2 neurons exhibit familiarity suppression. The effect develops over several days with a trajectory well fitted by an exponential function with a rate constant of similar to 100 exposures. Suppression occurs in V2 at a latency following image onset shorter than its reported latency in ITC.