Preliminary results from the new HIV surveillance system in France.
Preliminary results from the new HIV surveillance system in France.
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DOI：
10.2807/esm.09.10.00481-en
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发表时间：
2004-10-01
期刊：
影响因子：
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通讯作者：
Desenclos, J C
中科院分区：
文献类型：
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作者：
Lot, F;Semaille, C;Desenclos, J C
除了艾滋病监测之外，还需要关于艾滋病毒感染的数据，以便更好地跟踪这一流行病的动态。我们报告了法国强制性匿名艾滋病毒通报系统的第一批结果，该系统与对最近艾滋病毒感染和流行的艾滋病毒类型、群体和亚型的病毒学监测有关。艾滋病毒通知是由微生物学家发起的，他们创建了一个匿名的病人身份代码。临床医生填写流行病学和临床数据的通知表。除了艾滋病监测之外，还需要关于艾滋病毒感染的数据，以便更好地跟踪流行病的动态。我们报告了法国强制性匿名艾滋病毒通报系统的第一批结果，该系统与对最近艾滋病毒感染和流行的艾滋病毒类型、群体和亚型的病毒学监测有关。艾滋病毒通知是由微生物学家发起的，他们创建了一个匿名的病人身份代码。临床医生填写流行病学和临床数据的通知表。将样本送至当地卫生当局，并转交给Veille Sanitaire研究所（InVS）。实验室自愿将新诊断的艾滋病毒感染者的血清放在干血斑上送到国家艾滋病毒参考实验室，在那里进行最近感染（≤ 6个月）的免疫测定和血清分型测定，以确定群体和亚型。然后在InVS将病毒学结果与强制性报告的信息合并。在2003年报告的首批1 301例艾滋病毒新诊断病例中，43%为妇女，总体而言，53%为异性恋者，其中47%为撒哈拉以南非洲人。男男性行为者占男性通报的36%。64%的新艾滋病毒诊断可获得干血斑。38%的人有近期感染的证据，从注射吸毒者的22%到男男性行为者的58%不等。撒哈拉以南非洲移民中有26%的感染是最近感染的。HIV-1占所有报告的98%：其中48%是非B亚型。艾滋病毒通报系统的初步结果表明，异性性传播是主要的传播方式，来自撒哈拉以南非洲的人尤其受到影响。最近感染的病例中有一半以上是男男性行为者;这可能表明这一人群中艾滋病毒的发病率有所增加。
In addition to AIDS surveillance, data on HIV infection are necessary to better follow the dynamics of the epidemic. We report the first results of France's mandatory anonymous HIV notification system, which is linked to a virological surveillance of recent HIV infections and of circulating HIV types, groups and subtypes. HIV notifications are initiated by microbiologists who create an anonymous code of patient's identity. Clinicians complete the notification form with epidemiological and clinical data. Notifications are sent to the local health authorities and passed to the Institut de Veille Sanitaire (InVS).In addition to AIDS surveillance, data on HIV infection are necessary to better follow the dynamics of the epidemic. We report the first results of France's mandatory anonymous HIV notification system, which is linked to a virological surveillance of recent HIV infections and of circulating HIV types, groups and subtypes. HIV notifications are initiated by microbiologists who create an anonymous code of patient's identity. Clinicians complete the notification form with epidemiological and clinical data. Notifications are sent to the local health authorities and passed to the Institut de Veille Sanitaire (InVS). Laboratories voluntarily send sera from newly diagnosed HIV infected persons on dried blood spots to the national HIV reference laboratory where an immunoassay for recent infection (< or = 6 months) and a serotyping assay for the determination of group and subtype are done. The virological results are then merged at the InVS with the information from the mandatory reporting. Of the first 1301 new HIV diagnoses reported in 2003, 43% were in women, and overall, 53% were in heterosexuals, of whom 47% were of sub-Saharan African origin. MSM accounted for 36% of male notifications. A dried blood spot was available for 64% of new HIV diagnoses. Evidence of recent infection was found for 38%, ranging from 22% in IDUs to 58% in MSM. Twenty-six percent of infections in sub-Saharan migrants were recent infections. HIV-1 accounted for 98% of all notifications: 48% of these were non-B subtypes. The first results of the HIV notification system indicate that heterosexual transmission is the predominant mode of transmission and that persons originating from sub-Saharan Africa are particularly affected. Over half of infections shown to be recently acquired were in MSM; this may indicate an increased HIV incidence in this population.