The effect of oxygen and anaesthesia on radiosensitivity in vivo of epithelial cells of mouse skin.
The effect of oxygen and anaesthesia on radiosensitivity in vivo of epithelial cells of mouse skin.
复制标题
氧气和麻醉对小鼠皮肤上皮细胞体内放射敏感性的影响。
DOI：
10.1259/0007-1285-40-473-335
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发表时间：
1967
期刊：
影响因子：
--
通讯作者：
H. Withers
中科院分区：
文献类型：
--
作者：
H. Withers
使用原位克隆小鼠皮肤上皮细胞的技术，可以估计这些细胞在三个大气压下的氧气、空气和缺氧中的放射敏感性。本文讨论了麻醉对有氧辐射敏感性的影响。这些数据进行了比较，从观察皮肤的总反应，并与其他细胞类型的体内照射的结果。对小鼠皮肤上皮细胞内的氧张力进行了估计。
Using techniques for cloning skin epithelial cells in-situ in mice, it has been possible to estimate the radiosensitivity of these cells in oxygen at three atmospheres, in air, and in anoxia. The effect of anaesthesia on the aerobic radio-sensitivity is discussed. The data are compared with those obtained from observation of the gross response of skin and with results of irradiation in-vivo of other cell types. An estimate of oxygen tension within epithelial cells of mouse skin has been made.