SynBioHub: A Standards-Enabled Design Repository for Synthetic Biology
SynBioHub: A Standards-Enabled Design Repository for Synthetic Biology
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DOI：
10.1021/acssynbio.7b00403
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发表时间：
2018-02-01
影响因子：
4.7
通讯作者：
Wipat, Anil
中科院分区：
文献类型：
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作者：
McLaughlin, James Alastair;Myers, Chris J.;Wipat, Anil
SynBioHub存储库（synbiohub.org）是一个开源软件项目，旨在促进有关工程生物系统的信息共享。SynBioHub为软件和数据集成提供计算访问，并提供图形用户界面，使用户能够在Web浏览器中搜索和共享设计。通过连接到相关的存储库（例如，iGEM存储库、JBEI ICE和SynBioHub的其他实例），该软件允许用户浏览、上传和下载各种标准格式的数据，而不管它们的位置或表示。SynBioHub还为其他资源提供了一个中心参考点，使用合成生物学开放语言（SBOL）以标准化格式提供设计信息。SynBioHub的采用和使用是一项社区驱动的努力，通过帮助解决目前缺乏已发表设计信息的问题，有可能克服实验室之间的重现性挑战。
The SynBioHub repository (https://synbiohub.org) is an open-source software project that facilitates the sharing of information about engineered biological systems. SynBioHub provides computational access for software and data integration, and a graphical user interface that enables users to search for and share designs in a Web browser. By connecting to relevant repositories (e.g., the iGEM repository, JBEI ICE, and other instances of SynBioHub), the software allows users to browse, upload, and download data in various standard formats, regardless of their location or representation. SynBioHub also provides a central reference point for other resources to link to, delivering design information in a standardized format using the Synthetic Biology Open Language (SBOL). The adoption and use of SynBioHub, a community-driven effort, has the potential to overcome the reproducibility challenge across laboratories by helping to address the current lack of information about published designs.