Hydroxychloroquine as antiviral prophylaxis for exposed caregivers to Covid-19: An urgent appraisal is needed
Hydroxychloroquine as antiviral prophylaxis for exposed caregivers to Covid-19: An urgent appraisal is needed
复制标题
DOI：
10.1016/j.ijph.2020.05.005
复制
发表时间：
2020-06-01
影响因子：
6.7
通讯作者：
Bennis, Ahmed
中科院分区：
文献类型：
--
作者：
Hassani, Rachid Tahiri Joutei;Bennis, Ahmed
背景：新一轮冠状病毒大流行爆发以来，全球正面临着一场突发公共卫生事件。重新定位羟氯喹(HQ)似乎是一个有希望的选择。许多新出现的证据都集中在总部治疗新冠肺炎感染的有效性上。在最近的一篇论文中，Gautret等人。建议进一步确定总部的抗病毒预防措施是否有效，特别是对医务人员。方法：本文的目的是评估照顾者中新冠肺炎的暴露和风险水平。为此，计算机检索了Internet和PubMed数据库，检索词为：医护人员，医护人员，医生，护士，冠状病毒，新冠肺炎，死亡率，感染率，氯喹，羟基氯喹。结果：新冠肺炎关于医护人员感染和死亡的数据是部分的，没有系统地发表。然而，根据国家的不同，感染率似乎在3.8%到9%之间。而且该人群的平均年龄较高，尤其是在OECD地区。结论：抗新冠肺炎HQ预防措施亟待普及，尤其是医务人员。希望总部的预防措施能降低新冠肺炎感染在这一暴露尤其严重和相对较老的人群中的发病率和死亡率。(C)2020年，埃尔塞维尔有限公司代表沙特国王本·阿卜杜勒阿齐兹健康科学大学出版。
Background: Since the onset of the new coronavirus pandemic, the world is facing a public health emergency. Repositioning hydroxychloroquine (HQ) seems to be a promising option. Many emerging evidences have converged on the effectiveness of HQ in the treatment of Covid-19 infection. In a recent paper, Gautret et al. suggested that further works are needed to determine if HQ antiviral prophylaxis is useful, especially for healthcare workers.Methods: The purpose of this paper is to assess the Covid-19 exposure and risks level among caregivers. For this, we performed research on internet and PubMed by crossing the following keywords: healthcare givers, healthcare workers, doctors, nurses, coronavirus, Covid-19, mortality, infection rate, chloroquine, hydroxychloroquine.Results: Data on healthcare worker's infection and mortality by Covid-19 are partial and are not systematically published. However, it seems that the infection rate varies between 3.8% and 9% depending on the country. Moreover, the mean age of this population is relatively old, especially in the OECD area.Conclusions: Anti-Covid-19 HQprophylaxis should be urgently accessed, especially for healthcare workers. It is to be hoped that HQ prophylaxis reduces the morbidity and mortality from Covid-19 infection among this population which is particularly exposed and relatively old. (C) 2020 Published by Elsevier Ltd on behalf of King Saud Bin Abdulaziz University for Health Sciences.