First report of a novel abluminal groove filled biodegradable polymer rapamycin-eluting stent in de novo coronary artery disease: results of the first in man FIREHAWK trial

First report of a novel abluminal groove filled biodegradable polymer rapamycin-eluting stent in de novo coronary artery disease: results of the first in man FIREHAWK trial
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DOI:
10.3760/cma.j.issn.0366-6999.2012.06.003
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发表时间:
2012-03-20
影响因子:
6.1
通讯作者:
Gao Run-lin
Gao Run-lin
中科院分区:
医学2区
文献类型:
--
作者:
Qian Jie;Xu Bo;Gao Run-lin

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第一代药物洗脱支架(DES)使用的耐用聚合物可能导致持续性炎症和晚期DES血栓形成。我们报告了第一次在人类经验的雷帕霉素洗脱可生物降解聚合物涂层钴铬FIREHAWK支架与腔外groove.Methods共21例稳定或不稳定型心绞痛,或先前的心肌梗死,与单一的原发性冠状动脉狭窄
Background Durable polymers used for first-generation drug-eluting stents (DES) potentially contribute to persistent inflammation and late DES thrombosis. We report the first in human experience with the rapamycin-eluting biodegradable polymer coated cobalt-chromium FIREHAWK stent with abluminal groove.Methods A total of 21 patients with stable or unstable angina, or prior myocardial infarction, with single de novo native coronary stenoses