Definition of response and remission in children over one year of age with advanced neuroblastoma: proposition for a scoring system.
Definition of response and remission in children over one year of age with advanced neuroblastoma: proposition for a scoring system.
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一岁以上晚期神经母细胞瘤儿童的反应和缓解的定义：评分系统的提议。
DOI：
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发表时间：
1987
影响因子：
1.7
通讯作者：
O. Hartmann
中科院分区：
文献类型：
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作者：
T. Philip;L. Helson;J. Bernard;J. Zucker;Bernard Kremens;M. Favrot;O. Hartmann
提出了一个两步评估系统来分析1岁以上儿童IV期神经母细胞瘤的治疗结果。由于大多数方案包括一线化疗，随后是手术，通常是高剂量化疗和骨髓挽救，“反应”应评估单独化疗的效果，“缓解”表示尝试切除原发性肿瘤后的状态。一个评分系统，提出了这两个步骤。不同研究的可比性取决于使用这些共同标准来定义患者组和治疗结果。
A two-step evaluation system is proposed to analyze the results of therapy for stage IV neuroblastoma in children over 1 year of age. Since most protocols consist of first-line chemotherapy followed by surgery and often high-dose chemotherapy with bone marrow rescue, "response" should assess the effect of chemotherapy alone and "remission" indicate the status after an attempt to remove the primary tumor. A scoring system is proposed for both steps. The comparability of different studies depends on the use of such common criteria to define patient groups and treatment results.
影响因子：
158.5
作者：
SEEGER, RC;BRODEUR, GM;HAMMOND, D
通讯作者：
HAMMOND, D