Microbiological Diversity of Peri-Implantitis Biofilms
Microbiological Diversity of Peri-Implantitis Biofilms
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DOI：
10.1007/978-3-319-11038-7_5
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发表时间：
2015-01-01
期刊：
影响因子：
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通讯作者：
Feres, Magda
中科院分区：
文献类型：
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作者：
Faveri, Marcelo;Figueiredo, Luciene Cristina;Feres, Magda
开放式微生物诊断方法，例如通过桑格测序或焦磷酸测序对16S核糖体基因进行完全或部分测序，为口腔微生物群的多样性提供了新的见解。这些技术最近已被用于评估与骨结合种植体相关的微生物群，并且这些结果拓展了对与种植体周围炎相关的微生物群落多样性的认识。综合来看，这些研究的结果表明，种植体周围炎和牙周炎的微生物群落多样性可能并不像之前认为的那样相似。尽管某些已知的牙周病原体也可能与种植体周围炎的病因相关，但显然这两种临床状况之间存在许多差异，涉及不同的微生物。为了确定种植体周围炎有效的预防和治疗策略，对种植体周围微生物群多样性进行进一步研究将是至关重要的。标准化实验室操作规程也很重要，以便使基于PCR扩增的开放式诊断技术的结果在不同研究小组之间更具可比性。
The open-ended microbial diagnostic approaches such as the complete or partial sequencing of the 16S ribosomal gene by Sanger sequencing or by pyrosequencing have provided new insights into the diversity of the oral microbiota. These techniques have recently been used to evaluate the microbiota associated with osseointegrated implants and these results have expanded the knowledge on the diversity of the microbial communities associated with peri-implantitis. Taken together, the results of these studies suggest that the diversity of the microbial community of peri-implantitis and periodontitis might not be as similar as previously thought. Although certain known periodontal pathogens may also be associated with the etiology of peri-implantitis, apparently there were many differences between these two clinical conditions, involving distinct microorganisms. Further investigations on the diversity of peri-implant microbiota would be essential in order to define effective preventive and therapeutic strategies for peri-implantitis. It is also important to standardize laboratory protocols to make the results of the open-ended diagnostic techniques based on PCR amplification more comparable throughout the different research groups.