Sympathetic ophthalmia: an autoimmune ocular inflammatory disease

Sympathetic ophthalmia: an autoimmune ocular inflammatory disease
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DOI:
10.1007/bf00810245
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发表时间:
2004
期刊:
Springer Seminars in Immunopathology
影响因子:
--
通讯作者:
C. Chan;M. Mochizuki
C. Chan;M. Mochizuki
中科院分区:
其他
文献类型:
--
作者:
C. Chan;M. Mochizuki

文献摘要

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交感性眼炎是在一只眼睛的葡萄膜损伤后发生的双侧肉芽肿性全葡萄膜炎[20,29,57,89]。除了极少数的例外情况,这种损伤涉及创伤或手术引起的穿透伤。受伤的眼睛被称为兴奋眼或共病眼,而对侧的眼睛被称为同情眼。该疾病起病隐匿,病程进展,常出现加重期。这种疾病的组织病理学特征是由淋巴细胞和巨噬细胞组成的葡萄膜的结节性或弥漫性浸润[33]。
Sympathetic ophthalmia is a bilateral granulomatous panuveitis occurring after an injury to the uvea of one eye [20, 29, 57, 89]. With rare exceptions, the injury involves a penetrating wound resulting from trauma or surgery. The wounded eye is then termed the exciting or sympathogenic eye, and the contralateral eye is termed the sympathizing eye. The disorder has an insidious onset and a progressive course marked by frequent periods of exacerbation. This disease is characterized histopathologically by a nodular or diffuse infiltration of the uvea composed of lymphocytes and macrophages [33].