The dysfunction of processing task-irrelevant emotional faces in pituitary patients: an evidence from expression-related visual mismatch negativity

The dysfunction of processing task-irrelevant emotional faces in pituitary patients: an evidence from expression-related visual mismatch negativity
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垂体患者处理与任务无关的情绪面孔的功能障碍:来自表达相关视觉失配负性的证据

DOI:
10.1097/wnr.0000000000000965
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发表时间:
2018-03
期刊:
影响因子:
1.7
通讯作者:
Xu Guozheng
Xu Guozheng
中科院分区:
医学4区
文献类型:
--
作者:
Cao Chenglong;Song Jian;Yang Ming;Yao Shun;Yan Yan;Peng Guibao;Ma Pan;Huang Cheng;Ding Huichao;Xu Guozheng

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有证据表明,垂体腺瘤作为颅内肿瘤患者的认知能力受损。在本研究中,我们通过记录和分析异常情绪面孔引起的视觉失配负性来研究垂体腺瘤患者情绪面孔的前注意加工。在正常对照组中,异常的情绪面孔引起了表情相关的失配负波(EMMN),悲伤的负波比快乐的面孔更明显。与正常组相比,患者与悲伤面孔相关的EMMN较小,而与快乐面孔相关的EMMN保持不变。提示垂体腺瘤患者在注意前阶段存在负性情绪加工功能障碍。
Evidence showed impaired cognitive ability of patients with pituitary adenoma as an intracranial tumor. In the present study, we investigated the preattentive processing of emotional faces in pituitary adenoma patients by recording and analyzing the visual mismatch negativity elicited by deviant emotional faces. In the normal control group, deviant emotional faces elicited expression-related mismatch negativity (EMMN), with a more pronounced negative waveform for sad than happy face conditions. Compared with the normal group, EMMN related to sad faces was smaller in patients, whereas the EMMN related to happy faces remained the same. These data indicate the functional dysfunction of negative emotional processing at the preattentive stage of information processing in pituitary adenoma patients.
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