Considerations for the Design of Pre-exposure Prophylaxis (PrEP) Interventions for Women: Lessons Learned from the Implementation of a Novel PrEP Intervention.

Considerations for the Design of Pre-exposure Prophylaxis (PrEP) Interventions for Women: Lessons Learned from the Implementation of a Novel PrEP Intervention.
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DOI:
10.1007/s10461-021-03353-2
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发表时间:
2021-12
期刊:
影响因子:
4.4
通讯作者:
Blackstock OJ
Blackstock OJ
中科院分区:
医学2区
文献类型:
--
作者:
Walters SM;Platt J;Anakaraonye A;Golub SA;Cunningham CO;Norton BL;Sevelius JM;Blackstock OJ

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在美国,女性的暴露前预防(PrEP)摄入量一直很低。为了提高吸收率,我们开发了一种同伴外展和导航PrEP干预。半结构化定性访谈与32顺性别妇女和3变性妇女进行了评估干预。我们采用了主题方法来确定干预的障碍和促进因素。促进者包括对PrEP的兴趣,提供健康和社会服务,干预措施的以妇女为中心的方法,以及同行宣传和导航。这些障碍包括艾滋病毒风险、对药物副作用或相互作用的担忧、住房不安全和旅行、同时发生的与健康有关的疾病以及承担责任。我们建议未来的干预措施考虑在当地社区环境中包装PrEP,如注射器交换计划;包括食品和住房援助等服务;利用同龄人招募和教育妇女;纳入文化上适当的妇女重点;并考虑提供当天PrEP。
Pre-exposure prophylaxis (PrEP) uptake among women in the United States has been low. To increase uptake, we developed a peer outreach and navigation PrEP intervention. Semi-structured qualitative interviews with 32 cisgender women and 3 transgender women were conducted to assess the intervention. We used a thematic approach to identify barriers to, and facilitators of the intervention. Facilitators included interest in PrEP, offer of health and social services, the intervention’s women-focused approach, and peer outreach and navigation. Barriers were perceived HIV risk, concerns about medication side effects or interactions, housing insecurity and travel, co-occurring health-related conditions, and caregiving responsibilities. We recommend that future interventions consider packaging PrEP in local community settings, such as syringe exchange programs; include services such as food and housing assistance; use peers to recruit and educate women; integrate a culturally appropriate women’s focus; and consider providing same-day PrEP.
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