Personal exposure to fine particulate matter in elderly subjects: Relation between personal, indoor, and outdoor concentrations
Personal exposure to fine particulate matter in elderly subjects: Relation between personal, indoor, and outdoor concentrations
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DOI：
10.1080/10473289.2000.10464159
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发表时间：
2000-07-01
影响因子：
2.7
通讯作者：
Pekkanen, J
中科院分区：
文献类型：
--
作者：
Janssen, NAH;de Hartog, JJ;Pekkanen, J
荷兰阿姆斯特丹和芬兰赫尔辛基的老年心血管疾病受试者小组评估了环境水平、室内水平和个人暴露于PM2.5之间的时间序列相关性。对受试者进行为期6个月的两周临床访问。每名受试者在临床就诊前的24小时内，每两周测量一次PM2.5的室内和个人暴露情况。室外PM2.5浓度在固定地点进行测量。测量了所有PM2.5过滤器的吸收系数，作为元素碳(EC)的标志。分别对每个受试者进行回归分析，并调查个体回归系数和相关系数的分布。随着时间的推移，受试者体内的个人、室内和环境浓度高度相关。阿姆斯特丹和赫尔辛基的个人PM2.5与室外PM2.5之间的皮尔逊系数中值分别为0.79和0.76。在吸收方面，阿姆斯特丹和赫尔辛基的这两个值分别为0.93和0.81。这项研究的结果为在流行病学时间序列研究中使用固定地点测量作为PM2.5暴露的测量提供了进一步支持。
The time-series correlation between ambient levels, indoor levels, and personal exposure to PM2.5 was assessed in panels of elderly subjects with cardiovascular disease in Amsterdam, the Netherlands, and Helsinki, Finland. Subjects were followed for 6 months with biweekly clinical visits. Each subject's indoor and personal exposure to PM2.5 was measured biweekly, during the 24-hr period preceding the clinical visits. Outdoor PM2.5 concentrations were measured at fixed sites. The absorption coefficients of all PM2.5 filters were measured as a marker for elemental carbon (EC). Regression analyses were conducted for each subject separately, and the distribution of the individual regression and correlation coefficients was investigated. Personal, indoor, and ambient concentrations were highly correlated within subjects over time. Median Pearson's R between personal and outdoor PM2.5 was 0.79 in Amsterdam and 0.76 in Helsinki. For absorption, these values were 0.93 and 0.81 for Amsterdam and Helsinki, respectively. The findings of this study provide further support for using fixed-site measurements as a measure of exposure to PM2.5 in epidemiological time-series studies.