Electronic Cigarette Use and Myocardial Infarction Among Adults in the US Population Assessment of Tobacco and Health (Retracted Article)
Electronic Cigarette Use and Myocardial Infarction Among Adults in the US Population Assessment of Tobacco and Health (Retracted Article)
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DOI：
10.1161/jaha.119.012317
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发表时间：
2019-06-18
影响因子：
5.4
通讯作者：
Glantz, Stanton A.
中科院分区：
文献类型：
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作者：
Bhatta, Dharma N.;Glantz, Stanton A.
背景-电子烟是流行的戒烟和作为替代可燃香烟。我们评估了电子烟使用和有心肌梗死（MI）之间的关联，以及反向因果关系是否可以解释观察到的横截面之间的关联电子烟的使用和MI.Methods和Results-Cross-Section Analysis的人口评估烟草和健康波1之间的关联电子烟的使用和有和MI。纵向分析烟草和健康波1和2的人口评估的反向因果关系分析。进行逻辑回归以确定电子烟开始与MI之间的关联，调整吸烟，人口统计学和临床变量。每天的（调整后的比值比，2.25，95% CI：1.23-4.11）和某一天（1.99，95% CI：1.11-3.58）电子烟使用与MI的几率增加独立相关，具有显著的剂量反应（P0.62），这表明，反向因果关系不能解释在第1波观察到的电子烟使用和MI之间的横截面关联。白天使用电子烟与心肌梗死的风险增加有关，调整了可燃香烟吸烟。电子烟的效果与传统香烟相似，同时使用电子烟和传统香烟的风险比单独使用任何一种产品都要高。
Background-E-cigarettes are popular for smoking cessation and as an alternative to combustible cigarettes. We assess the association between e-cigarette use and having had a myocardial infarction (MI) and whether reverse causality can explain the observed cross-sectional association between e-cigarette use and MI.Methods and Results-Cross-sectional analysis of the Population Assessment of Tobacco and Health Wave 1 for association between e-cigarette use and having had and MI. Longitudinal analysis of Population Assessment of Tobacco and Health Waves 1 and 2 for reverse causality analysis. Logistic regression was performed to determine the associations between e-cigarette initiation and MI, adjusting for cigarette smoking, demographic and clinical variables. Every-day (adjusted odds ratio, 2.25, 95% CI: 1.23-4.11) and some-day (1.99, 95% CI: 1.11-3.58) e-cigarette use were independently associated with increased odds of having had an MI with a significant dose-response (P0.62), suggesting that reverse causality cannot explain the cross-sectional association between e-cigarette use and MI observed at Wave 1.Conclusions-Some-day and every-day e-cigarette use are associated with increased risk of having had a myocardial infarction, adjusted for combustible cigarette smoking. Effect of e-cigarettes are similar as conventional cigarette and dual use of e-cigarettes and conventional cigarettes at the same time is risker than using either product alone.