Evaluation of practice effect on neuropsychological measures among persons with and without HIV infection in northern India.
Evaluation of practice effect on neuropsychological measures among persons with and without HIV infection in northern India.
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DOI:
10.1007/s13365-016-0487-7
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发表时间:
2017-02
影响因子:
3.2
通讯作者:
Kumar M
中科院分区:
文献类型:
--
作者:
Ownby RL;Waldrop-Valverde D;Jones DL;Sharma S;Nehra R;Kumar AM;Prabhakar S;Acevedo A;Kumar M
An evaluation of the effects of HIV infection on neurocognition over time is important for understanding disease progression. Changes in cognitive function can be evaluated longitudinally using neuropsychological testing at repeated intervals. The assessment of change over time, however, is complicated by the potentially confounding influence of learning on repeated test administrations, often referred to as practice effect. In this study, we present data on testing of persons with or without HIV infection on a battery administered at study baseline and repeated one year later. Results suggest that practice effects may be diminished in persons with HIV infection compared to without it. This appears to be true even among those with relatively intact immune functioning as measured by CD4 count.