Influence of different surface machining treatments of resorbable magnesium alloy implants on degradation – EDX‐analysis and histology results

Influence of different surface machining treatments of resorbable magnesium alloy implants on degradation – EDX‐analysis and histology results
复制标题

可吸收镁合金植入物不同表面加工处理对降解的影响 – EDX 分析和组织学结果

DOI：
--
复制
发表时间：
2009
期刊：
影响因子：
--
通讯作者：
A. Meyer
A. Meyer
中科院分区：
--
文献类型：
--
作者：
N. Höh;B. Rechenberg;D. Bormann;A. Lucas;A. Meyer

文献摘要

被引文献

相似文献

圆柱形 MgCa0.8 种植体的表面经过不同的加工，形成光滑、喷砂和螺纹圆柱体的种植体。每组16个种植体植入新西兰白兔股骨内侧髁（共48只）。每一半植入物分别保留三个月和六个月。安乐死后，制作 5 μm 薄片，染色并通过半定量评分进行评估。每个表面的两个样本用于 EDX 分析。检查指定区域的预定元素的外观。 EDX 分析显示植入物边缘层含有磷。它出现在所有表面品种上。植入物附近的骨头中含有镁。它随着距植入部位距离的增加而减小。磷的出现表明种植体周围可能有新骨形成。这也表明良好的生物相容性和可能的​​骨诱导倾向。
The surface of cylindrical MgCa0.8 implants were differently machined which leads to smooth implants, sandblasted and threaded cylinders. 16 implants of each group were implanted into the medial femoral condylus of New Zealand White rabbits (totally n = 48). Each half of the implants remained for three and six months, respectively. After euthanasia 5 μm thin slices were produced, stained and evaluated through a semi quantitative scoring. Two specimen of each surface were used for EDX‐analysis. Specified areas were examined for the appearance of predetermined elements. The EDX‐analysis showed phosphorus in the edge layer of the implants. It appeared at all surface varieties. Magnesium could be found in the bone near the implants. It decreased with increasing distance to the implant site. The appearance of phosphorus indicates a possible new bone formation in the periphery of the implants. This also points to a good biocompatibility and a possible osteoinductive tendency.