Effects of serum 25-hydroxyvitamin D3 levels on physical fitness in community-dwelling frail women
Effects of serum 25-hydroxyvitamin D3 levels on physical fitness in community-dwelling frail women
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DOI：
10.1016/j.archger.2009.02.011
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发表时间：
2010-03-01
影响因子：
4
通讯作者：
Yanagi, Hisako
中科院分区：
文献类型：
--
作者：
Okuno, Junko;Tomura, Shigeo;Yanagi, Hisako
这项研究的目的是评估日本社区居住的虚弱老年人血清25-羟基维生素D-3(25(OH)D-3)水平和运动对身体健康的影响。在一个城镇(北纬368度)进行了纵向调查。80名年龄在65岁及以上的女性参加了为期3个月的健身班。在问卷调查的基础上进行了面对面的访谈。测定血清中完整甲状旁腺激素(IPTH)25(OH)D-3水平。在基线和3个月的随访期结束时进行了9项体能测试。在80名受试者中，56.3%的人在过去一年中经历过跌倒，71.3%的人经历过一次以上的绊倒。25(OH)D-3和25(OH)D-3<；50nmol/L和25(OH)D-3和75nmol/L的患病率分别为27.5%和88.8%。在课程结束时，25(OH)D-3水平大于67.5nmol/L(最高四分位数)的受试者在交替步幅、功能伸展(FR)、定时起跳(TUG)和5米步行(5米步行)方面有显著改善，并具有优越的功能能力。相比之下，25(OH)D-3水平和47.5nmol/L(最低四分位数)的受试者并没有改善他们的身体素质。因此，血清25(OH)D-3水平高于47.5nmol/L可能是维持步行能力和平衡所必需的。对于日本虚弱的老年妇女来说，大于67.5nmol/L似乎更适合于进行下肢力量训练。(C)2009爱思唯尔爱尔兰有限公司。保留所有权利。
The aim of this study was to evaluate the effects of a combination of serum 25-hydroxyvitamin D-3 (25(OH)D-3) levels and exercise on physical fitness in community-dwelling frail elderly in Japan. A longitudinal survey was conducted in a town (latitude 368 north). Eighty women aged 65 years and over attended a 3-month exercise class. A face-to-face interview was conducted based on a questionnaire. The serum levels of 25(OH)D-3, intact parathyroid hormone (iPTH), were measured. Nine physical fitness tests were performed at baseline and at the end of a 3-month follow-up period. Among 80 subjects, 56.3% experienced falls, and 71.3% experienced stumbling more than once during the past year. The prevalence of 25(OH)D-3 < 50 nmol/l or 25(OH)D-3 < 75 nmol/l was 27.5% and 88.8%, respectively. Significantly greater improvements in alternate step, functional reach (FR), "timed up & go" (TUG), and 5-m walk, and superior functional capacity for the subjects with 25(OH)D-3 levels greater than 67.5 nmol/l (highest quartile) was observed at the end of the class. In contrast, the subjects with 25(OH)D-3 levels < 47.5 nmol/l (lowest quartile) did not improve their physical fitness. A serum 25(OH)D-3 level of greater than 47.5 nmol/l may therefore be necessary to maintain walking ability and balance. Greater than 67.5 nmol/l appears to be preferable for lower extremity strength in Japanese frail elderly women. (C) 2009 Elsevier Ireland Ltd. All rights reserved.