Similar effects of repetitive transcranial magnetic stimulation of MT plus and a dorsomedial extrastriate site including V3A on pattern detection and position discrimination of rotating and radial motion patterns
Similar effects of repetitive transcranial magnetic stimulation of MT plus and a dorsomedial extrastriate site including V3A on pattern detection and position discrimination of rotating and radial motion patterns
复制标题
DOI：
10.1167/10.5.21
复制
发表时间：
2010-01-01
影响因子：
1.8
通讯作者：
Cowey, Alan
中科院分区：
文献类型：
--
作者：
Harvey, Benjamin M.;Braddick, Oliver J.;Cowey, Alan
我们最近的心理物理学实验已经确定了通过旋转、扩展和收缩刺激执行的模式检测和位置辨别任务的空间求和特征的差异。 MT 和 MST 区域已明确参与处理这些刺激。 fMRI 结果显示，V3A 区域的视网膜专题激活取决于视觉中径向运动中心的位置。这表明 V3A 可能参与具有这些运动模式的位置辨别任务。在这里，我们使用 MT+ 上的重复经颅磁刺激 (rTMS) 和包括 V3A 的背内侧纹状体区域来尝试区分 TMS 对模式检测和位置辨别任务的影响。如果 V3A 参与位置辨别，我们预计会看到对位置辨别任务的影响，但不会看到模式检测任务的影响，rTMS 作用于这个背内侧纹状体区域。事实上，我们无法将 TMS 对这两项任务的影响区分开来，这表明它们是由 MT+ 中的相同纹外区域执行的。
Our recent psychophysical experiments have identified differences in the spatial summation characteristics of pattern detection and position discrimination tasks performed with rotating, expanding, and contracting stimuli. Areas MT and MST are well established to be involved in processing these stimuli. fMRI results have shown retinotopic activation of area V3A depending on the location of the center of radial motion in vision. This suggests the possibility that V3A may be involved in position discrimination tasks with these motion patterns. Here we use repetitive transcranial magnetic stimulation (rTMS) over MT+ and a dorsomedial extrastriate region including V3A to try to distinguish between TMS effects on pattern detection and position discrimination tasks. If V3A were involved in position discrimination, we would expect to see effects on position discrimination tasks, but not pattern detection tasks, with rTMS over this dorsomedial extrastriate region. In fact, we could not dissociate TMS effects on the two tasks, suggesting that they are performed by the same extrastriate area, in MT+.