Creatine Supplementation Increases Total Body Water in Soccer Players: a Deuterium Oxide Dilution Study
Creatine Supplementation Increases Total Body Water in Soccer Players: a Deuterium Oxide Dilution Study
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DOI：
10.1055/s-0035-1559690
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发表时间：
2016-02-01
影响因子：
2.5
通讯作者：
Freitas, E.
中科院分区：
文献类型：
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作者：
Deminice, R.;Rosa, F. T.;Freitas, E.
本研究旨在评估足球运动员补充肌酸7天后，使用氧化氘稀释法和生物电阻抗（BIA）公式的全身水分（TBW）的变化。13名20岁以下健康足球运动员随机分为2组，安慰剂组（Pla，n=6）和肌酸补充组（CR，n=7）。分别于补饲前和补饲后（0.3g/kg/d，共7 d），用氧化氘稀释法和BIA法测定总体重。补充肌酸7天后，通过氧化氘稀释法测定的TBW大幅增加（2.3 +/-1.0L），与Pla相比，Cr组的总体重略有增加（1.0 +/-0.4kg）。Pla组TBW或体重未发生任何显著变化。尽管6个BIA方程中的5个对于确定肌酸补充引起的TBW变化敏感，但与氘稀释法相比，Kushner等人16的方法呈现了最佳的一致性水平。总之，7天的肌酸补充增加TBW确定的氧化氘稀释或BIA公式。BIA可用于确定足球运动员补充肌酸促进的TBW变化，特别关注配方的选择。
This study aimed to evaluate changes in total body water (TBW) in soccer athletes using a deuterium oxide dilution method and bioelectrical impedance (BIA) formulas after 7 days of creatine supplementation. In a double-blind controlled manner, 13 healthy (under-20) soccer players were divided randomly in 2 supplementation groups: Placebo (Pla, n=6) and creatine supplementation (CR, n=7). Before and after the supplementation period (0.3g/kg/d during 7 days), TBW was determined by deuterium oxide dilution and BIA methods. 7 days of creatine supplementation lead to a large increase in TBW (2.3 +/- 1.0L) determined by deuterium oxide dilution, and a small but significant increase in total body weight (1.0 +/- 0.4kg) in Cr group compared to Pla. The Pla group did not experience any significant changes in TBW or body weight. Although 5 of 6 BIA equations were sensitive to determine TBW changes induced by creatine supplementation, the Kushner et al. 16 method presented the best concordance levels when compared to deuterium dilution method. In conclusion, 7-days of creatine supplementation increased TBW determined by deuterium oxide dilution or BIA formulas. BIA can be useful to determine TBW changes promoted by creatine supplementation in soccer athletes, with special concern for formula choice.