CAPILLARY MICRO-ANEURYSMS IN THE HUMAN DIABETIC HEART

CAPILLARY MICRO-ANEURYSMS IN THE HUMAN DIABETIC HEART
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DOI:
10.1056/nejm198002143020706
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发表时间:
1980-01-01
影响因子:
158.5
通讯作者:
MINASE, T
MINASE, T
中科院分区:
医学1区
文献类型:
--
作者:
FACTOR, SM;OKUN, EM;MINASE, T

文献摘要

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在人心脏微循环的死后注射研究中,在胰岛素依赖型糖尿病患者的心脏中观察到典型的囊状和梭形微动脉瘤。为了证实最初的观察结果,研究了另外5名糖尿病患者。将这6例患者与8例血糖正常的非糖尿病对照组进行比较。在6例糖尿病患者中,3例患者的心脏中观察到微动脉瘤。微动脉瘤显然可能是一个更普遍的特点,糖尿病微循环比以前已经认识到。
During a post-mortem injection study of the human cardiac microcirculation, typical saccular and fusiform microaneurysms were observed in the heart of an insulin-dependent diabetic patient. To confirm initial observations, 5 additional diabetics were studied. These 6 patients were compared with 8 normoglycemic nondiabetic control subjects. Microaneurysms were observed in the hearts of 3 of the 6 diabetic patients. Microaneurysms evidently may be a more generalized feature of the diabetic microcirculation than has been previously recognized.