SYNTHESIS OF SOME NOVEL AND BIOLOGICALLY ACTIVE SCHIFF BASES BEARING A 1,3,4-THIADIAZOLE MOIETY UNDER ACIDIC AND PTC CONDITIONS
SYNTHESIS OF SOME NOVEL AND BIOLOGICALLY ACTIVE SCHIFF BASES BEARING A 1,3,4-THIADIAZOLE MOIETY UNDER ACIDIC AND PTC CONDITIONS
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酸性和 PTC 条件下合成一些带有 1,3,4-噻二唑部分的新颖且具有生物活性的席夫碱
DOI：
10.4067/s0717-97072011000300020
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发表时间：
2011
影响因子：
1.6
通讯作者：
A. Hamta
中科院分区：
文献类型：
--
作者：
A. Mobinikhaledi;M. Jabbarpour;A. Hamta
研究了通过 2-氨基-5-巯基-1,3,4-噻二唑与芳香醛在酸性和相转移催化剂 (PTC) 条件下反应合成一些带有 1,3,4-噻二唑基团 3a-1 的新型席夫碱。使用 FT-IR 和 NMR 光谱以及元素分析对所有席夫碱的结构进行了表征。研究了这些化合物对金黄色葡萄球菌（RTCC，1885）和大肠杆菌（ATCC，35922）的抗菌活性。
The synthesis of some new Schiff bases bearing a 1,3,4-thiadiazole moiety, 3a-l, by reaction of 2-amino-5-mercapto-1,3,4-thiadiazole with aromatic aldehydes under acidic and phase transfer catalyst (PTC) conditions was studied. The structure of all the Schiff bases was characterized using FT-IR and NMR spectroscopy, and elemental analyses. The antibacterial activity of these compounds was investigated against Staphylococcus aureus (RTCC, 1885), and Escherichia coli (ATCC, 35922).