Beetle horns evolved from wing serial homologs
Beetle horns evolved from wing serial homologs
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DOI：
10.1126/science.aaw2980
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发表时间：
2019-11-22
期刊：
影响因子：
56.9
通讯作者：
Moczek, Armin P.
中科院分区：
文献类型：
--
作者：
Hu, Yonggang;Linz, David M.;Moczek, Armin P.
了解新的复杂特征是如何起源的是进化生物学的一个基本挑战。我们调查了圣甲虫的前胸角的起源，圣甲虫是动物王国中第二性征最明显的例子之一。我们表明，prothoracic角来自双边源组织，不同的翅膀基因的功能需要指导这一过程，并在没有Hox输入，prothoracic角原基转化，以促进异位翅膀。然而，一旦诱导，前胸角的转录谱明显偏离翅膀和其他翅膀系列同源物。我们的研究结果证实了前胸角和昆虫翅膀之间的序列同源性，并表明其他昆虫的创新可能来自类似的翅膀系列同源物和随之而来的结构特异性转录景观的建立。
Understanding how novel complex traits originate is a foundational challenge in evolutionary biology. We investigated the origin of prothoracic horns in scarabaeine beetles, one of the most pronounced examples of secondary sexual traits in the animal kingdom. We show that prothoracic horns derive from bilateral source tissues; that diverse wing genes are functionally required for instructing this process; and that, in the absence of Hox input, prothoracic horn primordia transform to contribute to ectopic wings. Once induced, however, the transcriptional profile of prothoracic horns diverges markedly from that of wings and other wing serial homologs. Our results substantiate the serial homology between prothoracic horns and insects wings and suggest that other insect innovations may derive similarly from wing serial homologs and the concomitant establishment of structure-specific transcriptional landscapes.