COMPARISON BETWEEN NEAR-INFRARED SPECTROSCOPY AND XE-133 CLEARANCE FOR ESTIMATION OF CEREBRAL BLOOD-FLOW IN CRITICALLY ILL PRETERM INFANTS
COMPARISON BETWEEN NEAR-INFRARED SPECTROSCOPY AND XE-133 CLEARANCE FOR ESTIMATION OF CEREBRAL BLOOD-FLOW IN CRITICALLY ILL PRETERM INFANTS
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DOI：
10.1203/00006450-199301000-00012
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发表时间：
1993-01-01
影响因子：
3.6
通讯作者：
DUC, G
中科院分区：
文献类型：
--
作者：
BUCHER, HU;EDWARDS, AD;DUC, G
在9名需要机械通气和辅助供氧的危重早产儿（妊娠26-29周）中，通过近红外光谱和氙-133清除率对12次脑血流量进行了估计。在每项研究中，将氙-133测定的一次脑血流量与在1-19（中位数5）h内通过近红外进行的2 - 5次测量的平均值进行比较。 氙-133测量值范围为9.6-16.9 mL/100 g/min，平均近红外测量值范围为8.6-25.0 mL/100 g/min。两组测量值之间存在显著相关性（r = 0.80，p < 0.001）。两种方法之间的平均差异为1.6 mL/100 g/min，95%一致性限值为-0.5-3.8 mL/100 g/min。本研究表明，通过近红外光谱和氙-133清除技术，可以在床边无创地测量危重早产儿的脑血流量。这些方法给出了可比较的结果。
Estimations of cerebral blood flow were performed by both near infrared spectroscopy and xenon-133 clearance on 12 occasions in nine critically ill premature infants (26-29 gestational wk) who required mechanical ventilation and supplemental oxygen. For each study, one determination of cerebral blood flow by xenon-133 was compared with the mean of two to five measurements by near infrared done within 1-19 (median 5) h. Xenon-133 measurements ranged from 9.6-16.9 mL/100 g/min, and mean near infrared measurements ranged from 8.6-25.0 mL/100 g/min. There was a significant correlation between the two sets of measurements (r = 0.80, p < 0.001). The mean difference between the methods was 1.6 mL/100 g/min, and the 95% limits of agreement were -0.5-3.8 mL/100 g/min. This study showed that cerebral blood flow can be measured noninvasively in critically ill premature infants at the cotside by near infrared spectroscopy and by the xenon-133 clearance technique. The methods give comparable results.