Assessing IDU prevalence and health consequences (HCV, overdose and drug-related mortality) in a primary care trust: implications for public health action
Assessing IDU prevalence and health consequences (HCV, overdose and drug-related mortality) in a primary care trust: implications for public health action
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DOI：
10.1093/pubmed/fdp067
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发表时间：
2009-09-01
影响因子：
4.4
通讯作者：
Annett, Hugh
中科院分区：
文献类型：
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作者：
Hickman, Mathew;Hope, Vivian;Annett, Hugh
我们报道了一项评估单一初级保健信任中注射吸毒(IDU)及其相关危害的工作。协变量捕获-再捕获方法估计(I)IDU流行率；受访者驱动抽样测量(Ii)丙型肝炎病毒和艾滋病毒的流行率，并记录关联以衡量(Iii)死亡风险。(I)所有病例的注射毒品总估计数为5540例(95%可信区间，CI：4710-6780)，与初级保健登记匹配的病例为3280例(95%CI：1940-4610)，即15-54岁的流行率分别为2.2%和1.3%。(2)丙型肝炎病毒、乙肝病毒和艾滋病毒的流行率分别为53%、32%和0.7%。布里斯托尔超过70%的注射吸毒者报告至少接种过一次乙肝疫苗；超过一半的丙型肝炎阳性者没有被诊断出来。(3)注射吸毒者的全因死亡率和过量死亡率分别为0.75%和0.4%，标化死亡率为7.8%(95%可信区间：5.4~10.8)。
We report on an exercise to estimate the prevalence of injecting drug use (IDU) and associated harms in a single primary care trust.Covariate capture-recapture methods to estimate (i) IDU prevalence; respondent driven sampling to measure (ii) prevalence of HCV and HIV and record linkage to measure (iii) mortality risk.(i) The overall estimated number of IDU was 5540 (95% confidence interval, CI: 4710-6780) for all cases and 3280 (95% CI: 1940-4610) for cases matched to primary care register, i.e. a prevalence of 2.2 and 1.3% aged 15-54, respectively. (ii) The prevalence of HCV, hepatitis B and HIV was: 53, 32 and 0.7%. Over 70% of IDU in Bristol reported having at least one vaccination for HBV; more than half of those who were HCV positive were undiagnosed. (iii) The all-cause and overdose mortality rates for IDU were 0.75 and 0.4% respectively; and the standardized mortality ratio was 7.8 (95% CI: 5.4-10.8).Locally specific and useful intelligence on injecting and its health consequence can be generated to inform local public health action, and may contribute information to validate national prevalence estimates.