Comparison of treatment outcomes for Veterans with posttraumatic stress disorder with and without comorbid substance use/dependence
Comparison of treatment outcomes for Veterans with posttraumatic stress disorder with and without comorbid substance use/dependence
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DOI：
10.1016/j.jpsychires.2012.05.004
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发表时间：
2012-08-01
影响因子：
4.8
通讯作者：
Desai, Rani
中科院分区：
文献类型：
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作者：
Fontana, Alan;Rosenheck, Robert;Desai, Rani
大多数对患有共病物质使用/依赖障碍（SUD）和创伤后应激障碍（PTSD）的患者的治疗的关注都集中在SUD结果上。本研究的重点是共病患者的PTSD结果相比，那些只有PTSD。共有8599名退伍军人承认VA专门住院/住宅PTSD计划进行了评估，在入院时和出院后四个月的PTSD和SUD症状。由于第一份样品中的非预期结果，在不同阶段连续抽取两份样品：第一份样品中的4966份和第二份样品中的3633份。在第一个样本中，双重诊断的退伍军人比仅诊断为PTSD的退伍军人有更好的PTSD结果。这些差异主要归因于合并SUD症状的改善。这些结果在第二个样本中得到了重复。结果表明，可能有一个协同作用，在治疗这两种共病的疾病。爱思唯尔有限公司出版
Most of the attention to the treatment of patients who have comorbid Substance Use/Dependence Disorder (SUD) and Posttraumatic Stress Disorder (PTSD) has focused on SUD outcomes. This study focuses on the PTSD outcomes of comorbid patients as compared to those with PTSD only. Altogether 8599 Veterans admitted to VA specialized inpatient/residential PTSD programs were assessed for PTSD and SUD symptoms at admission and four months following discharge. Two samples were drawn sequentially in separate phases due to unexpected results in the first sample: 4966 in the first sample and 3633 in the second sample. In the first sample, dually diagnosed Veterans had significantly better PTSD outcomes than Veterans diagnosed with PTSD only. The differences could be attributed primarily to improvement in comorbid SUD symptoms. These results were replicated in the second sample. The results suggest that there may be a synergistic effect operating in the treatment of the two comorbid disorders. Published by Elsevier Ltd.