Doxycycline attenuated pulmonary fibrosis induced by bleomycin in mice
Doxycycline attenuated pulmonary fibrosis induced by bleomycin in mice
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DOI：
10.1128/aac.50.2.739-743.2006
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发表时间：
2006-02-01
影响因子：
4.9
通讯作者：
Nakanishi, Y
中科院分区：
文献类型：
--
作者：
Fujita, M;Ye, Q;Nakanishi, Y
The administration of doxycycline prior to bleomycin in mice attenuated pulmonary fibrosis. Bronchoalveolar neutrophil influx and gelatinase activity, but not caseinolytic activity, were attenuated by doxycycline. Established fibrosis was not affected by doxycycline. Thus, doxycycline might be useful for slowing down pulmonary fibrosis by biological activity other than antibacterial activity.
