Treatment options for human immunodeficiency virus-infected pregnant women. Obstetric-Gynecologic Working Group of the AIDS Clinical Trials Group of the National Institute of Allergy and Infectious Diseases.
Treatment options for human immunodeficiency virus-infected pregnant women. Obstetric-Gynecologic Working Group of the AIDS Clinical Trials Group of the National Institute of Allergy and Infectious Diseases.
复制标题
人类免疫缺陷病毒感染孕妇的治疗选择。
DOI：
10.1097/00006250-199203000-00024
复制
发表时间：
1992
影响因子：
7.2
通讯作者：
Stratton,P
中科院分区：
文献类型：
--
作者：
Sperling,RS;Stratton,P
由于育龄妇女人体免疫缺陷病毒（艾滋病毒）的血清流行率不断上升以及艾滋病毒垂直传播的危险，因此建议进行常规的产前艾滋病毒咨询和检测。进行此类检查的动机不仅与胎儿有关，而且与妇女早期综合治疗的潜在益处有关。怀孕期间应考虑使用的治疗方法包括抗逆转录病毒药物齐多夫定和预防卡氏肺囊虫肺炎的预防性药物，卡氏肺囊虫肺炎是进展为艾滋病的患者中最常见的机会性感染。在怀孕期间评估这些治疗的风险和益处是复杂的，需要医生和病人之间的讨论。本文回顾了目前的信息，并提供了建议，纳入治疗产科实践。（妇产科杂志1992；79:443-8）
: The increasing seroprevalence of human immunodeficiency virus (HIV) among women of reproductive age and the risks of vertical transmission of HIV have led to recommendations for routine prenatal HIV counseling and testing. The incentive to undergo such testing is related not only to fetal concerns, but also to the potential benefit of early and comprehensive therapy for women. Treatments that should be considered for use during pregnancy include the antiretroviral agent zidovudine and prophylactic agents to prevent Pneumocystis carinii pneumonia, the most common opportunistic infection seen in patients progressing to AIDS. Assessment of the risks and benefits of these treatments during pregnancy is complex and requires discussions between physician and patient. This paper reviews current information and provides recommendations for incorporating therapies into obstetric practice.(Obstet Gynecol 1992; 79: 443-8)