Characterization and in vitro properties of potentially probiotic Bifidobacterium strains isolated from breast-milk
Characterization and in vitro properties of potentially probiotic Bifidobacterium strains isolated from breast-milk
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DOI：
10.1016/j.ijfoodmicro.2010.10.036
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发表时间：
2011-09-01
影响因子：
5.4
通讯作者：
Gueimonde, Miguel
中科院分区：
文献类型：
--
作者：
Arboleya, Silvia;Ruas-Madiedo, Patricia;Gueimonde, Miguel
目前大多数商业益生菌菌株都不是针对特定应用而选择的，而是基于它们在各种应用中的技术潜力。因此，根据目标人群从适当的来源选择它们，可能会鉴定出性能更好的菌株。很少有菌株是专门为人类新生儿选择的，益生菌的应用可能会产生很大的积极影响。母乳是潜在的益生菌双歧杆菌的有趣来源，可用于婴儿配方奶粉和针对早产儿和足月婴儿的食品中。在这项研究中，从母乳中分离的6株双歧杆菌菌株根据国际益生菌指南进行了表型和基因表型表征。此外，采用不同的体外试验来评估菌株的安全性和益生菌潜力。尽管在对菌株的益生菌特性得出任何结论之前需要临床数据，但我们的研究结果表明，其中一些菌株可能具有益生菌潜力，可用于针对婴儿的产品。(C) 2010 Elsevier B.V.版权所有
Most of the current commercial probiotic strains have not been selected for specific applications, but rather on the basis of their technological potential for use in diverse applications. Therefore, by selecting them from appropriate sources, depending on the target population, it is likely that better performing strains may be identified. Few strains have been specifically selected for human neonates, where the applications of probiotics may have a great positive impact. Breast-milk constitutes an interesting source of potentially probiotic bifidobacteria for inclusion in infant formulas and foods targeted to both pre-term and full-term infants. In this study six Bifidobacterium strains isolated from breast-milk were phenotypically and genotypically characterised according to international guidelines for probiotics. In addition, different in vitro tests were used to assess the safety and probiotic potential of the strains. Although clinical data would be needed before drawing any conclusion on the probiotic properties of the strains, our results indicate that some of them may have probiotic potential for their inclusion in products targeting infants. (C) 2010 Elsevier B.V. All rights reserved.