GENE FLOW PAST A CLINE
GENE FLOW PAST A CLINE
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DOI：
10.1038/hdy.1979.86
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发表时间：
1979-01-01
期刊：
影响因子：
3.8
通讯作者：
BARTON, NH
中科院分区：
文献类型：
--
作者：
BARTON, NH
采用连续扩散模型研究了在紧密连锁的弱选择位点上，渐变群作为基因流屏障的效应。连锁渐变群诱导中性等位基因频率的一个阶跃，该阶跃与中性等位基因频率的梯度和重组率的倒数成正比。扩散的障碍或低丰度的局部区域具有类似的效果（Nagylaki，1976年）。该渐变群将阻断中性等位基因在染色体约2.5平方根区域上的流动。（s/t）地图单位长度。一个轻微的等位基因几乎不会受到影响，并且必须非常紧密地连锁才能被延迟很长时间。
The effect of a cline as a barrier to gene flow at closely linked, weakly selected loci is investigated using a continuous diffusion model. A linked cline induces a step in the frequency of a neutral allele, which is proportional to the gradient in neutral allele frequency and to the inverse of the recombination rate. A barrier to dispersal or a local region of low abundance has a similar effect (Nagylaki, 1976). The cline will block the flow of neutral alleles over a region of chromosome roughly 2.sqroot.(s/t) map units long. A slightly advantangeous allele will be little affected, and must be very tightly linked to be delayed for long.