The coexistence of thymic carcinoma and multiple granulomas in a Turkish child
The coexistence of thymic carcinoma and multiple granulomas in a Turkish child
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DOI：
10.1080/08880010701440882
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发表时间：
2007-01-01
影响因子：
1.7
通讯作者：
Sak, Serpil Dizbay
中科院分区：
文献类型：
--
作者：
Tacyildiz, Nurdan;Ugur, Handan;Sak, Serpil Dizbay
胸腺癌是一种具有明显细胞学异型性的胸腺上皮肿瘤，是一种罕见的肿瘤。作者报告了一名 10 岁男孩因前纵隔肿块而出现呼吸困难的情况。组织学和免疫组织化学研究证实了淋巴上皮瘤样胸腺癌。此外，对标本的评估显示胸腺组织内有干酪样变灶和多发性肉芽肿，中央广泛坏死。孩子接受了化疗，然后进行了手术和放疗。为了排除结核病的困扰，他还接受了抗结核治疗。停止治疗两年后，他的胸腺癌仍处于缓解期。
Thymic carcinoma, which is a thymic epithelial neoplasm with obvious cytologic atypia, is a rare neoplasm. The authors report on a 10-year-old boy who presented with respiratory distress due to bulky anterior mediastinal mass. Histological and immunohistochemical studies confirmed a lymphoepithelioma-like pattern thymic carcinoma. In addition, evaluation of the specimen showed foci of caseation and multiple granulomas with extensive central necrosis within the thymic tissue. The child received chemotherapy, followed by surgery and radiotherapy. To rule out difficulties of tuberculosis he also received antituberculosis therapy. Two years after cessation of treatment, he is still in remission for thymic carcinoma.