Correlation between Vitamin D deficiency and nonspecific chronic low back pain: A retrospective observational study.
Correlation between Vitamin D deficiency and nonspecific chronic low back pain: A retrospective observational study.
复制标题
维生素D缺乏与非特异性慢性腰痛的相关性：一项回顾性观察研究。
DOI：
10.4103/jfmpc.jfmpc_1478_20
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发表时间：
2021-03
影响因子：
1.4
通讯作者：
Neyaz O
中科院分区：
文献类型：
--
作者：
Kanaujia V;Yadav RK;Verma S;Jain S;Patra B;Neyaz O
慢性腰痛（CLBP）和维生素D缺乏是初级保健医生常见的两种情况。通过视觉模拟量表（VAS）研究非特异性CLBP患者的维生素D水平及维生素D水平与疼痛严重程度的相关性。一项观察性研究。回顾性分析2019年门诊就诊的所有CLBP患者的记录。所有年龄在18至65岁之间的非特异性CLBP患者均被纳入研究。将患者分为维生素D缺乏组（1组）和正常组（2组），血清维生素D值为30 ng/mL。记录两组患者的人口学资料和视觉模拟评分（VAS）。采用Spearman系数考察维生素D值与VAS评分的相关性，P≤0.05为显著性。在376名非特异性CLBP患者中，大多数是成年人、女性、已婚、素食者、超重或肥胖，平均日晒时间为2小时。维生素D缺乏组1有302例（80.32%）患者的平均维生素D水平显著低于组2（74例，19.68%）。维生素D与VAS的Spearman’s rho系数呈负相关（-0.554），P值< 0.00001。该研究表明，在非特异性CLBP人群中，维生素D缺乏的可能性很高，维生素D水平与疼痛严重程度呈负相关。
Chronic lower back pain (CLBP) and Vitamin D deficiency are two common conditions presenting to primary care physicians. To study the vitamin D status in North Indians presenting with nonspecific CLBP and the correlation between vitamin D levels and pain severity by the Visual Analogue Scale (VAS). An observational study. Record of all CLBP patients presenting to the outpatient department in 2019, were analyzed, retrospectively. All the patients of age 18 to 65 and either sex with nonspecific CLBP were included. Patients were divided into two: Vitamin D deficient (Group 1) and normal (Group 2) with cut off Serum Vitamin D values at 30 ng/mL. Demographic data and Visual Analogue Scale scores (VAS) of both groups were recorded. Correlations between Vitamin D values and VAS scores were investigated using the Spearman coefficient, and the results with P of ≤ 0.05 were contemplated significant. Of total 376 patients with nonspecific CLBP, the majority were adults, females, married, vegetarians, overweight or obese, and had a mean sun exposure time of two hours. Vitamin D deficient Group 1 had 302 (80.32%) patients with significantly lower (P < 0.0001) mean vitamin D levels compared to Group 2 (74 patients i.e., 19.68%). Spearman's rho coefficient between vitamin D and VAS, showed a negative correlation (–0.554), with a P value < 0.00001. This study indicated a high probability of vitamin D deficiency in the nonspecific CLBP population and a negative correlation between vitamin D status and pain severity.