ULTRASTRUCTURAL EVIDENCE FOR THE PRESENCE OF A GLIAL SHEATH INVESTING THE ISLETS OF LANGERHANS IN THE PANCREAS OF MAMMALS
ULTRASTRUCTURAL EVIDENCE FOR THE PRESENCE OF A GLIAL SHEATH INVESTING THE ISLETS OF LANGERHANS IN THE PANCREAS OF MAMMALS
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DOI：
10.1007/bf00217154
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发表时间：
1984-01-01
影响因子：
3.6
通讯作者：
DONEV, SR
中科院分区：
文献类型：
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作者：
DONEV, SR
超微结构证据表明，在不同哺乳动物的朗格汉斯岛周围存在岛周胶质细胞或雪旺细胞鞘。鞘覆盖了胰岛周围的大部分区域。沙鼠（Psammomys obesus）有胰岛，其中1/2至3/4的表面被几乎连续的胶质鞘覆盖。通常鞘覆盖在胰岛的一个极点上，因此与岛周结缔组织和胰腺腺泡有区别。鞘由位于胰岛外围的单个卫星细胞的长而薄的外生物组成。鞘是单层的，沿着连续束的过程，其宽度从不超过20-40纳米，因此通过增加细胞间隙的电子密度的方法更充分地展示了它。先前对胰岛单个内分泌细胞周围胶质鞘的描述仅代表岛周鞘的一小部分。胰岛卫星细胞与自主神经节的卫星细胞明显不同，但与髓外副神经节的卫星细胞更为相似。
Ultrastructural evidence is presented for a peri-insular glial or Schwann cell sheath surrounding islets of Langerhans in different mammals. The sheath covers substantial areas of the islet periphery. In the sand rat (Psammomys obesus) there are islets where 1/2 to 3/4 of the surface is invested by a virtually continuous glial sheath. Usually the sheath covers one of the poles of the islets and is thus differentiated from the peri-insular connective tissue and pancreatic acini. The sheath is composed of long, exceptionally thin outgrowths of single satellite cells located at the periphery of the islets. The sheath is a monolayer and, along the course of continuous tracts, its width never exceeds 20-40 nm, hence its more adequate demonstration by methods that increase the electron density of the intercellular spaces. Previous descriptions of glial sheaths surrounding single endocrine cells in the islets represent only a fragment of the peri-insular sheath. The islet satellite cells differ significantly from those of autonomic ganglia but resemble more closely those found in extramedullary paraganglia.