Architecture of the pulmonary veins:: relevance to radiofrequency ablation
Architecture of the pulmonary veins:: relevance to radiofrequency ablation
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DOI：
10.1136/heart.86.3.265
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发表时间：
2001-09-01
期刊：
影响因子：
5.7
通讯作者：
Sánchez-Quintana, D
中科院分区：
文献类型：
--
作者：
Ho, SY;Cabrera, JA;Sánchez-Quintana, D
背景-射频消融肺静脉内组织可消除阵发性心房颤动。目的-探讨正常肺静脉的特点，为射频消融提供更多的相关信息。方法-20例结构正常的心脏标本进行大体检查。从65个肺静脉组织切片。结果最长的心肌袖被发现在上级静脉。左上级肺静脉的静脉心房交界处的袖套最厚。对于上级静脉，袖套沿下壁沿着最厚，向上最薄。袖状结构主要由环形或斜向肌细胞束组成，另外还有纵向或斜向肌细胞束，有时形成网状排列。纤维化的变化，估计在5%和70%之间的三个横截面被认为是从个人年龄在30至72岁的17条静脉。结论在正常肺静脉的心肌结构是高度可变的。纤维化的复杂排列、拉伸和增加可产生更大的非均匀各向异性特性。
Background-Radiofrequency ablation of tissues in pulmonary veins can eliminate paroxysmal atrial fibrillation.Objective-To explore the characteristics of normal pulmonary veins so as to provide more information relevant to radiofrequency ablation.Methods-20 structurally normal heart specimens were examined grossly. Histological sections were made from 65 pulmonary veins.Results-The longest myocardial sleeves were found in the superior veins. The sleeves were thickest at the venoatrial junction in the left superior pulmonary veins. For the superior veins, the sleeves were thickest along the inferior walls and thinnest superiorly. The sleeves were composed mainly of circularly or spirally oriented bundles of myocytes with additional bundles that were longitudinally or obliquely oriented, sometimes forming mesh-like arrangements. Fibrotic changes estimated at between 5% and 70% across three transverse sections were seen in 17 veins that were from individuals aged 30 to 72 years.Conclusions-The myocardial architecture in normal pulmonary veins is highly variable. The complex arrangement, stretch, and increase in fibrosis may produce greater non-uniform anisotropic properties.