Synergistic Effect of Apple Extracts and Quercetin 3-β-D-Glucoside Combination on Antiproliferative Activity in MCF-7 Human Breast Cancer Cells in Vitro

Synergistic Effect of Apple Extracts and Quercetin 3-β-D-Glucoside Combination on Antiproliferative Activity in MCF-7 Human Breast Cancer Cells in Vitro
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DOI:
10.1021/jf8039796
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发表时间:
2009-09-23
影响因子:
6.1
通讯作者:
Liu, Rui Hai
Liu, Rui Hai
中科院分区:
农林科学1区
文献类型:
--
作者:
Yang, Jun;Liu, Rui Hai

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乳腺癌是女性中最常见的癌症。通过测量MCF-7人乳腺癌细胞50 (CI)值在50%和95%抑制率分别为0.76 +/- 0.16和0.42 +/- 0.10时,苹果提取物和Q3G的DRI值分别达到50% +/- 0.55和4.28 +/- 0.39倍,来评估降低(Q3G)的替代策略。结果表明
Breast cancer is the most frequently diagnosed cancer in women. An alternative strategy to reduce the (Q3G) was assessed by measurement of the inhibition of MCF-7 human breast cancer cell 50 (CI) values at 50 and 95% inhibition rates were 0.76 +/- 0.16 and 0.42 +/- 0.10, (DRI) values of the apple extracts and Q3G to achieve a 50% +/- 0.55 and 4.28 +/- 0.39-fold, respectively. The results suggest