Correlation of Headache Frequency and Psychosocial Impairment in Migraine: A Cross-Sectional Study
Correlation of Headache Frequency and Psychosocial Impairment in Migraine: A Cross-Sectional Study
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DOI：
10.1111/head.12195
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发表时间：
2014-05-01
期刊：
影响因子：
5
通讯作者：
Straube, Andreas
中科院分区：
文献类型：
--
作者：
Ruscheweyh, Ruth;Mueller, Melanie;Straube, Andreas
目的探讨头痛频率每月15天是否构成偏头痛相关心理社会损害的转折点。背景偏头痛根据头痛频率标准（< vs >每月≥ 15个头痛日）分为发作性和慢性形式。目前尚不清楚该标准是否代表了该疾病的临床和病理生理学意义的转折点。方法601例偏头痛患者完成了疼痛特异性残疾（偏头痛残疾评估量表，von Korff量表）、健康相关生活质量（简表-12健康调查表）、习惯性幸福感（马尔堡问卷）和焦虑和抑郁（医院焦虑和抑郁评分）的测量。结果头痛频率越低，心理社会功能障碍越明显，而头痛频率越高，心理社会功能障碍越明显。目视检查和样条插值表明，转折点并不完全是每月15个头痛日，而是大约13.3天（置信区间：8.9-17.7）。因此，头痛天数与心理社会损害之间的显著相关性在以下组中被发现：
Objective To investigate if a headache frequency of 15 days per month constitutes a turning point in the psychosocial impairment associated with migraine. Background Migraine is differentiated into episodic and chronic forms based on a headache frequency criterion (< vs >= 15 headache days per month). It is presently not clear if this criterion represents a clinically and pathophysiologically meaningful turning point of the disease. Methods Six hundred and one migraine patients completed measures of pain-specific disability (Migraine Disability Assessment Scale, von Korff scale), health-related quality of life (Short Form-12 Health Survey), habitual well-being (Marburg questionnaire), and anxiety and depression (Hospital Anxiety and Depression Score). Results A significant increase of psychosocial impairment with the number of headache days per month was found at lower headache frequencies, but leveled off at higher headache frequencies. Visual inspection and spline interpolation suggested that the turning point was not exactly at 15 headache days per month but rather around 13.3 (confidence interval: 8.9-17.7) days. Accordingly, significant correlations between headache days and psychosocial impairment were found in the group with