Vertical Nanowire Electrode Arrays as Novel Electrochemical Label-Free Immunosensors.
Vertical Nanowire Electrode Arrays as Novel Electrochemical Label-Free Immunosensors.
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DOI:
10.1002/smll.201403540
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发表时间:
2015-06
期刊:
影响因子:
13.3
通讯作者:
Babak Nasr;Gursharan Chana;Ting Ting Lee-Ting;T. Nguyen;C. Abeyrathne;G. D'Abaco;M. Dottori;E. Skafidas
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文献类型:
--
作者:
Babak Nasr;Gursharan Chana;Ting Ting Lee-Ting;T. Nguyen;C. Abeyrathne;G. D'Abaco;M. Dottori;E. Skafidas
A new method for the fabrication of a label-free electrochemical immunosensor based on vertical nanowires (VNWs) is proposed. The VNWs are functionalized to detect antibodies against a major astrocytic structural protein component, glial fibrillary acidic protein (GFAP). It is revealed that the interaction of GFAP-antibody with functionalized VNWs leads to a clear change in device conductance and the corresponding capacitance.