Quality of life and work in patients with rheumatoid arthritis and ankylosing spondylitis of working age
Quality of life and work in patients with rheumatoid arthritis and ankylosing spondylitis of working age
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DOI：
10.1136/ard.2002.004861
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发表时间：
2003-12-01
影响因子：
27.4
通讯作者：
van der Linden, S
中科院分区：
文献类型：
--
作者：
Chorus, AMJ;Miedema, HS;van der Linden, S
目的：目的：探讨16- 59岁类风湿关节炎（RA）和强直性脊柱炎（AS）患者工作与生活质量的关系。方法：对1056例RA和658例AS患者进行调查。数据通过邮寄问卷获得，其中包括几个通用和疾病相关的生活质量工具。比较SF-36的单独维度和身心总分。采用逐步多元回归分析方法研究工作与身心健康相关QOL的关系，包括疾病相关因素、应对方式、疲劳等。结果：工作年龄组RA患者的身心健康相关QOL较AS患者差，心理健康相关QOL较好。RA和AS之间没有差异，发现躯体疼痛，身体功能，社会功能，情感功能，活力，或一般健康感知;也没有任何显着差异，疲劳和行为应对方式。在两组中，工作与身体健康相关的生活质量呈正相关，并且在疾病特征之后，是最重要的决定因素。没有发现与心理健康相关的QOL.Conclusions：虽然身体健康相关的QOL是更糟糕的RA患者，健康相关的QOL的几个方面的影响RA和AS的工作年龄下的风湿护理是可比的。类风湿关节炎和强直性脊柱炎患者在身体角色功能（包括工作）方面经历了类似的限制。工作是身体健康相关生活质量的重要独立外部决定因素，但不是心理健康相关生活质量的重要独立外部决定因素。
Objective: To investigate the relationship between work and quality of life (QOL) in patients with rheumatoid arthritis (RA) and ankylosing spondylitis (AS) aged 16-59.Methods: 1056 patients with RA and 658 with AS were included in the study. Data were obtained by postal questionnaire, which included several generic and disease related QOL instruments. Separate dimensions and physical and mental summary scores from the SF-36 were compared. Stepwise multiple regression was performed to study the relationship between work and physical and mental health related QOL, including disease related factors, coping, and fatigue.Results: Physical health related QOL was reported to be worse, and mental health related QOL better, in RA than in AS in people of working age. No differences between RA and AS were found in somatic pain, physical role functioning, social functioning, emotional role functioning, vitality, or general health perception; nor were there any significant differences in fatigue and behavioural coping styles. Work was positively associated with physical health related QOL in both groups and, after disease characteristics, was the most important determinant. No association was found with mental health related QOL.Conclusions: Although physical health related QOL was worse in patients with RA, the impact on several dimensions of health related QOL in patients with RA and AS of working age under rheumatological care was comparable. Patients with RA and AS experienced similar limitations in physical role functioning, including work. Work is an important independent external determinant of physical health related QOL, but not of mental health related QOL.