CARDIOVASCULAR-RESPONSES DURING THE MENOPAUSAL HOT FLUSH
CARDIOVASCULAR-RESPONSES DURING THE MENOPAUSAL HOT FLUSH
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DOI：
10.1111/j.1471-0528.1981.tb02230.x
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发表时间：
1981-01-01
期刊：
影响因子：
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通讯作者：
OREILLY, B
中科院分区：
文献类型：
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作者：
GINSBURG, J;SWINHOE, J;OREILLY, B
通过体积描记技术测量自发性和应激诱导的绝经期[人类]潮红期间的循环反应。随着症状的出现，手部血流量立即显著增加，持续3-4分钟，然后再过3分钟降至控制水平。前臂和小腿血流同时增加，但程度较小，并在症状出现后4.5分钟内恢复控制水平。平均脉搏率也增加，在冲洗，但下降到控制值时，肢体血流仍然升高。在冲洗期间或冲洗后，血压没有显著变化。外周循环的改变归因于自主神经活动的改变，可能部分反映了绝经期体温调节控制的紊乱，潮红只是其中的一种表现。
Circulatory responses during spontaneous and stress-induced menopausal [in humans] flushes were measured by a plethysmographic technique. With the onset of symptoms there was an immediate and marked increase in hand blood flow which was sustained over 3-4 min and then fell to control levels over a further 3 min. Forearm and calf flow increased simultaneously though to a lesser extent and regained control levels within 4.5 min from the onset of symptoms. Mean pulse rate also increased during the flush but fell to control values at a time when limb flow was still elevated. There was no significant change in blood pressure during or after the flush. The peripheral circulatory changes are attributed to altered autonomic activity and may in part reflect a disturbance of thermoregulatory control in the menopause of which the flush is but one manifestation.