A metal-free turn-on fluorescent probe for the fast and sensitive detection of inorganic azides.
A metal-free turn-on fluorescent probe for the fast and sensitive detection of inorganic azides.
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DOI：
10.1016/j.bmcl.2016.02.069
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发表时间：
2016-04-01
影响因子：
2.7
通讯作者：
Wang B
中科院分区：
文献类型：
--
作者：
Wang K;Friscourt F;Dai C;Wang L;Zheng Y;Boons GJ;Wang S;Wang B
叠氮化钠是有毒的，广泛用于农业，商业产品和研究实验室。因此，它是一个重要的环境问题，需要开发一种快速检测方法。本文描述了荧光二苄基环辛炔衍生物（F1-DIBO）作为荧光探针，用于通过应变促进的叠氮化物-炔环加成（SPAAC）快速检测无机叠氮化物。与其它常见阴离子相比，Fl-DIBO对NaN 3具有很高的选择性，灵敏度高，检出限为10 μM。
Sodium azide is toxic and widely used in agricultural, commercial products, and research laboratories. Thus it is of a significant environmental concern and there is a need for the development of a rapid detection method. A fluorogenic dibenzylcyclooctyne derivative (Fl-DIBO) is herein described as a fluorescent probe for the rapid detection of inorganic azide via Strain-Promoted Azide-Alkyne Cycloaddition (SPAAC). Fl-DIBO was found to be highly selective toward NaN3 in comparison to other common anions with good sensitivity and detection limit of 10 μM.