Compositional design and optimization of dentin adhesive with neutralization capability.
Compositional design and optimization of dentin adhesive with neutralization capability.
复制标题
具有中和能力的牙本质粘合剂的成分设计与优化。
DOI：
10.1016/j.jdent.2015.06.008
复制
发表时间：
2015
影响因子：
4.4
通讯作者：
Spencer,Paulette
中科院分区：
文献类型：
--
作者：
Song,Linyong;Ye,Qiang;Ge,Xueping;Spencer,Paulette
ObjectivesThe objective of this work is to investigate the polymerization behavior，neutralization capability，and mechanical properties of dentin adhesive formulations with addition of the tertiary amine co-monomer，2-N-morpholinoethyl methacrylate（MEMA.MethodsA co-monomer mixture based on HEMA/BisGMA（45/55，w/w）was used as a control adhesive.与对照配方相比，含MEMA的粘合剂配方的特征在于全面关于液体树脂的水溶性、固化聚合物的吸水性和溶解性、实时光聚合动力学、动态力学分析（DMA）和调制差示扫描量热法（MDSC）。的中和能力，其特征在于通过监测1 mM的乳酸（LA）溶液的pH值的变化，在其中的粘合剂聚合物被浸泡。ResultsWith增加MEMA浓度，实验共聚物表现出较高的吸水性，较低的玻璃化转变温度和较低的交联密度相比，控制。LA溶液的pH值在90天后从3.5逐渐增加到约6.0-6.5。随着共聚物交联密度的增加，中和速率降低。最佳MEMA浓度为20和40重量%之间。ConclusionsAs相比，对照，结果表明，MEMA功能化的共聚物显示中和能力。共聚物网络的交联密度影响中和速率。
ObjectivesThe objective of this work was to investigate the polymerization behavior, neutralization capability, and mechanical properties of dentin adhesive formulations with the addition of the tertiary amine co-monomer, 2-N-morpholinoethyl methacrylate (MEMA).MethodsA co-monomer mixture based on HEMA/BisGMA (45/55, w/w) was used as a control adhesive. Compared with the control formulation, the MEMA-containing adhesive formulations were characterized comprehensively with regard to water miscibility of liquid resin, water sorption and solubility of cured polymer, real-time photopolymerization kinetics, dynamic mechanical analysis (DMA), and modulated differential scanning calorimetry (MDSC). The neutralization capacity was characterized by monitoring the pH shift of 1 mM lactic acid (LA) solution, in which the adhesive polymers were soaked.ResultsWith increasing MEMA concentrations, experimental copolymers showed higher water sorption, lower glass transition temperature and lower crosslinking density compared to the control. The pH values of LA solution gradually increased from 3.5 to about 6.0–6.5 after 90 days. With the increase in crosslinking density of the copolymers, the neutralization rate was depressed. The optimal MEMA concentration was between 20 and 40 wt%.ConclusionsAs compared to the control, the results indicated that the MEMA-functionalized copolymer showed neutralization capability. The crosslinking density of the copolymer networks influenced the neutralization rate.