Toward a wide-field retinal prosthesis.
Toward a wide-field retinal prosthesis.
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DOI：
10.1088/1741-2560/6/3/035002
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发表时间：
2009-06
影响因子：
4
通讯作者：
Weiland JD
中科院分区：
文献类型：
--
作者：
Ameri H;Ratanapakorn T;Ufer S;Eckhardt H;Humayun MS;Weiland JD
本文的目的是提出一种宽场电极阵列，可以增加植入视网膜假体的患者的视野。低视力患者的活动能力通常受损，特别是那些周边视力丧失的患者。对低视力患者的研究以及对正常视力个体的模拟研究表明，视野和移动性之间存在很强的相关性。此外，已经表明，增加的视野与视敏度和物体辨别力的显著改善相关。目前植入动物或人类的电极阵列大小不同;然而，电极覆盖的视网膜区域具有约10°的最大投影视野。我们已经设计了宽场电极阵列，其可以潜在地提供34°的视野，这可以显著地提高移动性。在机械眼模型上进行的测试表明，可以使用单个视网膜钉将10 mm宽的柔性聚酰亚胺虚拟电极阵列固定到视网膜上。他们还表明，阵列可以符合眼睛的内部曲率。在摘除的猪眼模型上进行的surgery证明了通过5 mm眼壁切口植入10 mm宽阵列的可行性。
The purpose of this article is to present a wide field electrode array that may increase the field of vision in patients implanted with a retinal prosthesis. Mobility is often impaired in patients with low vision, particularly in those with peripheral visual loss. Studies on low vision patients as well as simulation studies on normally sighted individuals have indicated a strong correlation between the visual field and mobility. In addition, it has been shown that increased visual field is associated with a significant improvement in visual acuity and object discrimination. Current electrode arrays implanted in animals or human vary in size; however, the retinal area covered by the electrodes has a maximum projected visual field of about 10°. We have designed wide field electrode arrays that could potentially provide a visual field of 34°, which may significantly improve the mobility. Tests performed on a mechanical eye model showed that it was possible to fix flexible polyimide dummy electrode arrays of 10 mm wide onto the retina using a single retinal tack. They also showed that the arrays could conform to the inner curvature of the eye. Surgeries on an enucleated porcine eye model demonstrated feasibility of implantation of 10 mm wide arrays through a 5 mm eye wall incision.
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影响因子：
4
作者：
Loudin, J. D.;Simanovskii, D. M.;Palanker, D. V.
通讯作者：
Palanker, D. V.
DOI：
10.1109/tnsre.2005.848687
发表时间：
2005-06-01
影响因子：
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作者：
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通讯作者：
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通讯作者：
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DOI：
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发表时间：
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影响因子：
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通讯作者：
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影响因子：
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作者：
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通讯作者：
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