Statistics and dynamics of procaryotic cell populations
Statistics and dynamics of procaryotic cell populations
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DOI：
10.1016/0025-5564(67)90008-9
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发表时间：
1967-01-01
期刊：
影响因子：
--
通讯作者：
TSUCHIYA, H. M.
中科院分区：
文献类型：
--
作者：
FREDERICKSON, A. G.;RAMKRISHNA, D.;TSUCHIYA, H. M.
细胞群体的数学理论的形成需要能够定量地确定群体中单个细胞的生理状态。在原核细胞(细菌和蓝藻)中，细胞内结构具有相对简单的性质，推测这种细胞的生理状态是由其生化成分决定的。如果细胞的生长速度及其分裂概率仅取决于细胞的当前生理状态和细胞环境的当前状态，则可以推导出种群中生理状态分布的变化方程。此外，还可以得到蜂窝环境状态的变化方程。这些方程允许根据通过分析细胞和亚细胞结构和功能获得的信息来预测细胞群体的统计和动态行为。|抽象作者：作者
The formation of a mathematical theory of a cell population requires the ability to specify quantitatively the physiological state of individual cells of the population. In procaryotic cells (bacteria and blue-green algae), the intracellular structure is of a relatively simple nature, and it is postulated that the physiological state of such a cell is specified by its biochemical composition. If the growth rate of a cell and its fission probability depend only on the cell's current physiological state and on the current state of the cell's environment, then an equation of change for the distribution of physiological states in a population can be derived. In addition,an equation of change for the state of the cellular environment can be obtained. These equations allow prediction of the statistical and dynamical behavior of a cell population from information obtained by analysis of cellular and subcellular structure and function. || ABSTRACT AUTHORS: Authors