Increasing prevalence of Japanese cedar pollinosis: A meta-regression analysis
Increasing prevalence of Japanese cedar pollinosis: A meta-regression analysis
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DOI：
10.1159/000084256
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发表时间：
2005-01-01
影响因子：
2.8
通讯作者：
Eboshida, A
中科院分区：
文献类型：
--
作者：
Kaneko, Y;Motohashi, Y;Eboshida, A
背景：日本柳杉花粉病是由日本柳杉树（Crypomeria japonica）的花粉引起的，是日本最常见的季节性过敏性疾病。关于日本柳杉花粉病的流行病学调查已有许多报道，但从未对其进行系统或定量的评估。为了确认日本柳杉花粉病的患病率不断上升以及相关因素，我们对日本基于人口的调查进行了荟萃回归分析。方法：我们从基于人群的调查中检索数据，其中使用血清学方法对所有参与者进行测试。使用对数转换患病率和致敏率的加权回归来评估调查年份、年龄和城市化程度的影响。我们还分析了患病率和致敏率之间的关系。结果：从1986年至2000年发表的文献中筛选出38份报告，涉及27个流行亚组和134个致敏率亚组。发现日本柳杉花粉致敏率与调查年份、年龄和城市化程度显着相关（调整后的R-2 = 0.55）。患病率和致敏率之间的相关系数显示出统计学上显着的相关性（Pearson's r = 0.70，p < 0.001）。结论：根据估计的致敏率以及致敏率与流行率之间的关系，预测2004年日本柳杉花粉病在大城市地区青少年中的患病率为28.7%，在城市地区一般人群中为24.5%。 1980年至2000年间，日本柳杉花粉病的流行率增加了2.6倍，并且流行率根据年龄和城市化程度而有很大差异。版权所有 (C) 2005 S. Karger AG，巴塞尔。
Background: Japanese cedar pollinosis, caused by the pollen of the Japanese cedar tree ( Cryptomeria japonica), is the commonest seasonal allergic disease in Japan. A number of epidemiological surveys have been reported on Japanese cedar pollinosis, but it has never been assessed systematically or quantitatively. To confirm the increasing prevalence of Japanese cedar pollinosis and related factors, we conducted a meta-regression analysis on population-based surveys in Japan. Methods: We searched for data from population-based surveys in which serological methods were used to test all participants. Weighted regression of logit-transformed prevalence and sensitization rates were used to evaluate the effects of the year of survey, age, and degree of urbanization. We also analyzed the relationship between prevalence and sensitization rate. Results: Thirty-eight reports with 27 subgroups for prevalence and 134 subgroups for sensitization rate were selected from the literature published in the years between 1986 and 2000. The Japanese cedar pollen sensitization rate was found to be significantly correlated with the year of survey, age, and degree of urbanization (adjusted R-2 = 0.55). The coefficient for the correlation between the prevalence and the sensitization rate revealed a statistically significant correlation (Pearson's r = 0.70, p < 0.001). Conclusions: The prevalence of Japanese cedar pollinosis among adolescents was predicted to be 28.7% in metropolitan areas and 24.5% in the general population in urban areas in the year 2004, derived from the estimated sensitization rate and the relationship between sensitization rate and prevalence. The prevalence of Japanese cedar pollinosis increased 2.6-fold between 1980 and 2000, and the prevalence differed considerably according to age and degree of urbanization. Copyright (C) 2005 S. Karger AG, Basel.