Deep brain stimulation in Tourette's syndrome
Deep brain stimulation in Tourette's syndrome
复制标题
DOI：
10.1002/mds.21398
复制
发表时间：
2007-07-15
影响因子：
8.6
通讯作者：
Leckman, James F.
中科院分区：
文献类型：
--
作者：
Bajwa, Rizma Jalees;de Lotbiniere, Alain J.;Leckman, James F.
一名48岁男性，患有严重的、终身性抽动秽语综合征（TS），其特征是强有力的自我伤害性运动抽搐和强迫症，采用双侧脑深部电刺激（DBS）治疗。治疗的决定是基于他的进行性神经损伤（继发于脊髓损伤的左侧无力），因为他的无情，暴力的头部抽搐。将电极植入丘脑内侧部分（中央中核、室周质和腹口核）的水平。DBS导致抽搐大幅减少。这些数据表明，双侧丘脑DBS对患有难治性TS的成人患者的严重联系有良好的效果。(c)2007运动障碍协会
A 48-year-old man with severe, lifelong Tourette's syndrome (TS) characterized by forceful self-injurious motor tics and, obsessive-compulsive disorder was treated with bilateral deep brain stimulation (DBS). The decision to treat was based on his progressive neurological impairment (left sided weakness secondary to spinal cord injury) because of his relentless, violent head jerks. Electrodes were implanted at the level of the medial part of the thalamus (centromedian nucleus, the substantia periventricularis, and the nucleus ventro-oralis interims). DBS resulted in a substantial reduction of tics. These data show that bilateral DBS of the thalamus can have a good effect on severe ties in adult patients suffering from intractable TS. (c) 2007 Movement Disorder Society